Wasps star Andrea Masi has been ruled out for up to five months after suffering a knee injury against Sale last month.
Alasdair Strokosch's converted try in the final minute gave Scotland a 30-29 success over Italy.
Scotland name three changes to their line-up ahead of the final Quadrangular Tournament clash against Italy in Pretoria.
Scotland scrum coach Massimo Cuttitta is confident his men can compete with the Italian pack.
Samoa resisted an early storm to triumph 39-10 over Italy and reach the Quadrangular Tournament final in South Africa.
Italy name seven changes to their line-up ahead of Saturday's quadrangular series encounter with Samoa in Nelspruit.
South Africa ran in five tries to record a 44-10 win over Italy at the King's Park Rugby Stadium on Saturday.
Treviso fly-half Alberto Di Bernardo will make his Italy debut in Saturday's Test against South Africa in Durban.
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